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Crossref · failed DataCite · 20 found DOAJ · 20 found Europe PMC · deferred capacity
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Journal ArticleOpen access

The AST/ALT ratio as a mediator of heavy metal exposure and diabetic kidney disease (DKD) risk: A NHANES study

Yu Li; Juan Chai; Jinjuan Chen; Jiayin Du; Jianbo Mu; Lingqin Zhang2025

Scientific Reports

Online resource

DOI
10.1038/s41598-025-23843-w
Abstract

Abstract The potential impact of heavy metal exposure on the progression of diabetic kidney disease (DKD) remains a subject of scientific inquiry. While some studies have hinted at a correlation, definitive evidence is still lacking.

Diabetic kidney diseaseHeavy metalMetal mixturesMediation analysisNHANES
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Journal ArticleOpen access

The M235T polymorphism in the angiotensinogen gene is not a major risk factor for diabetic nephropathy; a meta-analysis

Bhuneshwar Sahu; Shashikant Swarnakar; Henu Kumar Verma; Thavanati Parvathi Kumara Reddy; Smaranika Pattnaik; Bhaskar VKS Lakkakula2022

Journal of Preventive Epidemiology

Online resource

DOI
10.34172/jpe.2022.15
Abstract

Introduction: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease in diabetes patients. The angiotensin AGT M235T gene polymorphism, which is linked to the renin-angiotensin-aldosterone system (RAAS), has been extensively studied in DN patients, but the results are still conflicting.

chronic kidney diseaseend-stage renal diseasediabetic nephropathymeta-analysisSpecialties of internal medicine
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Journal ArticleOpen access

A Liquid-Based Cytology System, without the Use of Cytocentrifugation, for Detection of Podocytes in Urine Samples of Patients with Diabetic Nephropathy

Moritsugu Kimura; Masao Toyoda; Nobumichi Saito; Noriko Kaneyama; Han Miyatake; Eitaro Tanaka; Hirotaka Komaba; Masanori Hara; Masafumi Fukagawa2019

Journal of Diabetes Research

Online resource

DOI
10.1155/2019/9475637
Abstract

Desquamated podocytes can be detected in urine of patients with severe renal impairment. Unlike the rapidly progressive glomerular damage in glomerulonephritis, only a few desquamated podocytes are usually detected in diabetic nephropathy (DN).

Diseases of the endocrine glands. Clinical endocrinology
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Journal ArticleOpen access

Microenvironment‐adaptive nanodecoy synergizes bacterial eradication, inflammation alleviation, and immunomodulation in promoting biofilm‐associated diabetic chronic wound healing cascade

Lei Chen; Mengna Peng; Wei He; Xiaoli Hu; Jian Xiao; Linqi Shi; Yong Liu; Yuanfeng Li2024

Aggregate

Online resource

DOI
10.1002/agt2.640
Abstract

Abstract The presence of bacterial biofilms and the occurrence of excessive inflammatory response greatly imped the healing process of chronic wounds in diabetic patients. However, effective strategies to simultaneously address these issues are still lacking.

biofilmchronic woundinflammatory cytokinesreactive oxygen speciessynergy therapy
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Journal ArticleOpen access

Insufficient Expression of Cyclooxygenase-2 Protein Is Associated With Retarded Degradation of Aggregated Protein in Diabetic Glomeruli

Yasushi Hirasawa; Aiko Muramatsu; Yoshio Suzuki; Tadashi Nagamatsu2006

Journal of Pharmacological Sciences

Online resource

DOI
10.1254/jphs.fpj06010x
Abstract

To elucidate the involvement of cyclooxygenase (COX) in degradation of aggregated protein in diabetic glomeruli, we used streptozotocin (STZ)-induced diabetic mice and aggregated bovine serum albumin (a-BSA) as a model protein.

Therapeutics. Pharmacology
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Journal ArticleOpen access

Relating aqueous to vitreous humor proteomics for identification of reliable biomarkers in proliferative diabetic retinopathy

Ingeborg Klaassen; Michael W.T. Tanck; Holly J. Duncan; Elif Yildiz; Reinier O. Schlingemann; David Steel2026

Newcastle University

Online resource

DOI
10.25405/ncl.34552368
Abstract

© The Author(s) 2026. This study aimed to identify aqueous humor (AQ) proteins that correlate with vitreous humor (VH) levels in proliferative diabetic retinopathy (PDR).

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Journal ArticleOpen access

Relating aqueous to vitreous humor proteomics for identification of reliable biomarkers in proliferative diabetic retinopathy

Ingeborg Klaassen; Michael W.T. Tanck; Holly J. Duncan; Elif Yildiz; Reinier O. Schlingemann; David Steel2026

Newcastle University

Online resource

DOI
10.25405/ncl.34552368.v1
Abstract

© The Author(s) 2026. This study aimed to identify aqueous humor (AQ) proteins that correlate with vitreous humor (VH) levels in proliferative diabetic retinopathy (PDR).

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Journal ArticleOpen access

Differential Expression of Serum TUG1, LINC00657, miR-9, and miR-106a in Diabetic Patients With and Without Ischemic Stroke

Omayma O Abdelaleem; Olfat G. Shaker; Mohamed M. Mohamed; Tarek I. Ahmed; Ahmed F. Elkhateeb; Noha K. Abdelghaffar; Naglaa A. Ahmed; Abeer A. Khalefa; Nada F. Hemeda; Rania H. Mahmoud2022

Frontiers in Molecular Biosciences

Online resource

DOI
10.3389/fmolb.2021.758742
Abstract

Non-coding RNAs are established as promising biomarkers for diabetes and its complications. The present research investigated the expression profiles of serum TUG1, LINC00657, miR-9, and miR-106a in diabetic patients with and without stroke.Methods: A total of 75 diabetic patients without stroke, 77 patients with stroke, and 71 healthy controls were recruit…

TUG1LINC00657miR-9miR-106astroke
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Journal ArticleOpen access

Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis

Sowrabha Bhat; Subhodip Pramanik; Pradip Mukhopadhyay; Subhankar Chowdhury2021

Journal of Clinical and Diagnostic Research

Online resource

DOI
10.7860/jcdr/2021/48795.15099
Abstract

Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes. Diabetic Ketoacidosis (DKA) is a rare but known complication of diabetes in acromegaly.

growth hormone excessketosispituitary macroadenomaMedicine
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Journal ArticleCheck access

Hypoglycemic oral effective dose of methanol root extract of tacazzea apiculata (oliv) on alloxan-induced diabetic mice and its safety potentials on sub-chronic administration

Ogochukwu Offu2026

Newcastle University

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DOI
10.25405/ncl.34549689
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Journal ArticleCheck access

Hypoglycemic oral effective dose of methanol root extract of tacazzea apiculata (oliv) on alloxan-induced diabetic mice and its safety potentials on sub-chronic administration

Ogochukwu Offu2026

Newcastle University

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DOI
10.25405/ncl.34549689.v1
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The impact of National Health Insurance Scheme on Clinical Parameters of Diabetic and Hypertensive civil servants and retirees in South-East Nigeria

Ogochukwu Offu2026

Newcastle University

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DOI
10.25405/ncl.34549695
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The impact of National Health Insurance Scheme on Clinical Parameters of Diabetic and Hypertensive civil servants and retirees in South-East Nigeria

Ogochukwu Offu2026

Newcastle University

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DOI
10.25405/ncl.34549695.v1
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Journal ArticleOpen access

The Advances of Single-Cell RNA-Seq in Kidney Immunology

Honghui Zeng; Xiaoqiang Yang; Siweier Luo; Yiming Zhou2021

Frontiers in Physiology

Online resource

DOI
10.3389/fphys.2021.752679
Abstract

Here, we discuss several recent studies using scRNA-seq technology to explore the immune-related kidney diseases, including lupus nephritis, diabetic kidney disease, IgA nephropathy, and anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.

kidneyimmune systemsingle-cell RNA sequencinglupus nephritisdiabetic kidney disease
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Journal ArticleOpen access

SPECTRUM: Early clinical experience from the first global real-world study of aflibercept 8 mg in patients with diabetic macular oedema

Clare Bailey; Marion R. Munk; Varun Chaudhary; Clemens Lange; Hassiba Oubraham; Peter Morgan-Warren; Helmut Allmeier; Tobias Machewitz; Sarah Schlief; Rose Gilbert; Susanne Oesch; Martin Kirchner; Zoran Hasanbasic; Paolo Lanzetta; Hani Hasan2026

Newcastle University

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DOI
10.25405/ncl.34550805
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Journal ArticleOpen access

SPECTRUM: Early clinical experience from the first global real-world study of aflibercept 8 mg in patients with diabetic macular oedema

Clare Bailey; Marion R. Munk; Varun Chaudhary; Clemens Lange; Hassiba Oubraham; Peter Morgan-Warren; Helmut Allmeier; Tobias Machewitz; Sarah Schlief; Rose Gilbert; Susanne Oesch; Martin Kirchner; Zoran Hasanbasic; Paolo Lanzetta; Hani Hasan2026

Newcastle University

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DOI
10.25405/ncl.34550805.v1
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Book ChapterCheck access

The role of exercise and physical activity in diabetic neuropathy

Mallikarjuna Pichika2026

Newcastle University

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The role of exercise and physical activity in diabetic neuropathy

Mallikarjuna Pichika2026

Newcastle University

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Novel Biomarkers for early diagnosis of diabetic neuropathy: Current research and prospects

Mallikarjuna Pichika2026

Newcastle University

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Novel Biomarkers for early diagnosis of diabetic neuropathy: Current research and prospects

Mallikarjuna Pichika2026

Newcastle University

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