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Finally, we will talk about the ecological significance and evolutionary advantage of cryptic BGCs’ role in interactions between microorganisms, such as competition, communication, symbiosis and environmental adaptability, so as to provide a useful background for accelerating next-generation antibiotics.

© The Author(s) 2026.Parkinson’s disease (PD) exhibits highly heterogeneous clinical trajectories, yet “advanced PD” (aPD) lacks a standardized definition. Current reliance on clinical milestones (e.g., motor fluctuations, cognitive decline) is limited by non-linear progression and the absence of objective measures.

© The Author(s) 2026.Parkinson’s disease (PD) exhibits highly heterogeneous clinical trajectories, yet “advanced PD” (aPD) lacks a standardized definition. Current reliance on clinical milestones (e.g., motor fluctuations, cognitive decline) is limited by non-linear progression and the absence of objective measures.

This study explored Next Generation Science Standards (NGSS) in cross-cultural biology teaching through collaborative lesson studies involving educators from the USA and the Philippines.

The observation of Earth’s gravity field was successfully performed by the GRACE and GOCE satellite missions, and will be continued by the GRACE Follow-On mission. A comprehensive team of European scientists proposed the next-generation gravity field mission MOBILE in response to the European Space Agency (ESA) call for a Core Mission in the frame of Earth…

Next-generation sequencing was used to compare these gene sequences with those from a large, normal population. In this study, we identified 19 gene variants that were present at significantly lower frequencies in our Italian cohort than in the general population.

Crucially, the DSGC enables a 1.74 times energy output boost compared to conventional compressors. These findings establish the DSGC as a pivotal advancement for next-generation ultrahigh-power laser systems, providing a viable pathway toward hundreds of PW output through optimized spatial energy redistribution.

SiPMs possess single-photon resolution capability and time resolution below 100 ps, enabling precise photon arrival time measurements. These advances paved the way for emerging applications such as time-of-flight PET (TOF-PET), photon counting CT, and positron emission lifetime imaging, presenting new challenges to SiPM performance, the advancing of which t…

Representative scaffolds, including chromen-4-one derivatives and next-generation clinical candidates such as AZD7648 and VX-984, are discussed. Finally, we summarise current clinical progress in early phase trials and remaining challenges, including achieving tolerability and efficacy when compounds are administered both as a single agent, or in combinatio…

Representative scaffolds, including chromen-4-one derivatives and next-generation clinical candidates such as AZD7648 and VX-984, are discussed. Finally, we summarise current clinical progress in early phase trials and remaining challenges, including achieving tolerability and efficacy when compounds are administered both as a single agent, or in combinatio…

Polygonum is a generalized genus of the Polygonaceae family that includes various herbaceous plants. In order to provide aid in understanding the evolutionary and phylogenetic relationship in Polygonum at the chloroplast (cp) genome-scale level, we sequenced and annotated the complete chloroplast genomes of four Polygonum species using next-generation seque…

Next-generation internet technologies, represented by artificial intelligence, are reshaping the nationwide health information distribution system; this study examines the synergistic benefit effect of online health communication on health promotion.

Electromagnetic field (EMF) exposure mapping is increasingly important for ensuring compliance with safety regulations, supporting the deployment of next-generation wireless networks, and addressing public health concerns.

Abstract In this paper, the problem of opportunistic spectrum sharing for the next generation of wireless systems empowered by the cloud radio access network (C‐RAN) is studied. More precisely, low‐priority users employ cooperative spectrum sensing to detect a vacant portion of the spectrum that is not currently used by high‐priority users.

© 2026 The Author(s). Arthritis & Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology.Objective: CD4 T cells specific for citrullinated (cit) peptides are key players in rheumatoid arthritis (RA) immunopathogenesis.

© 2026 The Author(s). Arthritis & Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology.Objective: CD4 T cells specific for citrullinated (cit) peptides are key players in rheumatoid arthritis (RA) immunopathogenesis.

The deposition of suspended sediment is an important process that helps wetlands accrete surface material and maintain elevation in the face of sea level rise. Optical remote sensing is often employed to map total suspended solids (TSS), though algorithms typically have limited transferability in space and time due to variability in water constituent compos…

In this paper we present analytical performance evaluation of a dual-hop OFDM amplify-andforward (AF) variable gain (VG) relay system implementing ordered subcarrier mapping (SCM) at the relay station (R), considered to be a very interesting solution for the next generation mobile cellular networks.